Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep286 | Calcium and Vitamin D metabolism | ECE2015

Thalassemia-induced osteoporosis and bisphosphonate treatment: a systematic review and meta-analysis

Tsartsalis Athanasios , Lambrou George , Savvidis Christos , Chrousos George , Kattamis Antonis

Introduction: Osteopenia and osteoporosis develop with aging in thalassemia patients despite clinical treatment therapy has improved. Bisphosphonates, which are potent inhibitors of osteoclastic bone resorption, have been recently used to correct the bone abnormality in thalassemia with encouraging results. Bisphosphonates are a class of drugs that prevent the loss of bone mass, used to treat osteoporosis and similar diseases. They are the most commonly prescribed drugs used t...